Extended-Release Injectable Naltrexone (TIP 49, Chapter 5)

From Incorporating Alcohol Pharmacotherapies Into Medical Practice (TIP 49)

About the Course:

Many health problems or mental disorders that healthcare practitioners (particularly those in primary care) encounter in their everyday practices derive from or are complicated by alcohol use disorders (AUDs). Consequently, healthcare practitioners are in key positions to manage the care of large numbers of individuals with AUDs. However, only a small percentage of these patients are actually treated for AUDs in these settings. The publication, Incorporating Alcohol Pharmacotherapies Into Medical Practice, discuses medications currently approved for treating alcohol use disorders (AUDs). Chapter Five  presents detailed information about extended-release injectable naltrexone.

Course materials are from Chapter Five found on pages 37-44 of the pdf document (pages 53-60 if using Adobe toolbar page finder.) Course materials can be accessed either 1) online or by ordering the publication free of charge from:


U.S. Department of Health and Human Services

Publication Date:



U.S. Department of Health and Human Services

Recommended For:

This course is recommended for health care professionals, especially addiction counselors, psychologists, mental health counselors, social workers, and nurses who seek knowledge about the usage of extended-release injectable naltrexone for the treatment of alcohol use disorders. It is appropriate for all levels of participants’ knowledge.

Course Objectives:

  1. Describe the history, pharmacology, efficacy, and safety of extended-release injectable naltrexone as a treatment for alcohol use disorders.

  2. Discuss the clinical usage of injectable naltrexone including administration, side effects, patient management, and patient education. 

  3. Identify patients appropriate for injectable naltrexone treatment, and discuss treatment duration and discontinuation. 

Exam Questions

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